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International Scientific Indexing (ISI) Indexed Journal Applied Medical Research ISSN: 2149 - 2018

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Applied Medical Research. 2024; 11(2):(153-176)
doi: doi.org/10.47363/AMR/2024(11)236


Oncology Breakthroughs to A New Pace of Precision Diagnostics and Therapeutics

Hung-Chih Lai, Wen-Hung Kuo and Chen Yeh*

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Abstract
Background: When it comes to developing new cancer diagnostics (Dx) and therapeutics (Rx), time is of the essence-for the patients that need treatments most, every day counts. Traditional benchmarks of Dx and Rx have delivered favorable clinical outcomes on a slower timeline than patients can afford.


Methods: Transformative Dx tools such as liquid biopsy in combination with next-generation sequencing (NGS) have emerged as a standard of care to inform clinical decision, treatment response and prognosis much sooner.

Results: As the cutting-edge Dx technology continues to advance, it will complement Rx innovation like antibody-drug conjugates (ADCs), chimeric antigen receptor T-cell (CAR-T) therapy and messenger RNA (mRNA) medicine, and help lifesaving treatments reach patients earlier than ever.

Conclusions: Highly personalized Dx and Rx breakthroughs can empower providers and researchers alike with precise and real-world data on each patients’ cancer, helping them to develop and deliver real-time precision oncology care.