Applied Medical Research. 2020;
7(2):(76-154)
Changes in Synaptic Terminal Structure in Adolescent Rat during Pregnancy; the Action Potential Propagation and Synaptic Transmission
Opeyemi Oluwasanmi Adeloye*, Oyeneyin Babatunde David, Samuel Olawuwo and Roseline kehinde Adeloye
Abstract
Synaptic plasticity is a biological system of specific pattern of synaptic activity result
in changes in synaptic strength. This influence puberty, pregnancy hormones, sensory
experiences, and brain disorders. Long-term synaptic plasticity is accompanied by protein
synthesis and trafficking, leading to structural changes of the synapse. Increasing evidence
connects the terminal synaptic changes with potential propagation in adolescent and
pregnancy. We investigate on the synaptic structural plasticity, which has mainly been
studied with in vivo two-photon laser scanning microscopy. We also discuss how a different
type of synapses, the multi-contact synapses associated with pregnancy.
